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The International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA) came into being in 1999 from the particularly felt need of sharing know-how, objectives and results between areas that until then seemed quite distinct such as bioengineering, medicine and singing. MAVEBA deals with all aspects concerning the study of the human voice with applications ranging from the neonate to the adult and elderly. Over the years the initial issues have grown and spread also in other aspects of research such as occupational voice disorders, neurology, rehabilitation, image and video analysis. MAVEBA takes place every two years always in Firenze, Italy.
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The effectiveness of ten different feature sets in classification of voice recordings of the sustained phonation of the vowel sound /a/ into a healthy and pathological classes is investigated as well as a non approach to building a sequential committee of support vector machines (SVM) for the classifications is proposed. The optimal values of hyperparameters of the committee and the feature sets providing the best performance are found during the genetic search. In the experimental investigations performed using 444 voice recordings of the sustained phonation of the vowel sound /a/ coming from 148 subjects, three recordings from each subject, the correct classification rate of over 92 % was obtained. The classification accuracy has been compared with the accuracy obtained from four human experts.
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The ability of non-equilibrium plasmas to modify surfaces has been known for many years. And a promising way to perform surface modifications without altering the bulk properties is plasma polymerization since this technique is versatile and can be applied to a wide range of materials. Plasma polymer films usually show good biocompatibility when compared to classical biomaterials. The possible biomedical use of plasma polymers motivates the study of their behavior during storage and in aqueous environment. Therefore, it is of major importance to understand the change of properties of these plasma polymers over time and when in contact with certain fluids. Recently, plasma polymer gradients (surfaces that display a change in at least one physicochemical property over distance) have attracted significant attention from the biomedical filed where the interaction of cells with a material surface is of major interest. This chapter discusses biomaterial functionalization via plasma polymerization focusing on their use in the biomedical field as well as their aging and stability behaviors. Plasma polymer gradients as valuable tools to investigate cell-surface interactions will also be reviewed.
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Biomedical engineering --- Cybernetics --- Biomedical Engineering. --- Cybernetics.
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